5 (127 Reviews)

Retinol

Preserved Retinol, Maximum Performance.
This treatment visibly reduces wrinkles and fine lines, plumps the skin, and deeply hydrates. A complete care dedicated to skin longevity:

  • 0.1% pure retinol concentration
  • Hyaluronic acid
  • Astaxanthin
  • ↑ Radiance
  • ↑ Texture
  • ↑ Hydration
  • ↓ Dark spots
  • ↓ Imperfections
Purchase options How It Works
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DUOLAB Technology guarantees:

0% active ingredient degradation for 100% efficacy with every application
The Minilab creates a fresh emulsion in seconds, ensuring optimal penetration of active ingredients into the targeted layers of the skin
Precise dosing. Never too much.

What's in the box

1 Minilab device (on loan)

Your Minilab, simply

For any DUOLAB treatment, your Minilab device is provided free of charge for 3 months.

And if you order a new treatment during that period, your loan is automatically extended.

At the end of your treatment, simply return the Minilab by post or directly to:

HOME OF DUOLAB
1 Rue Étienne-Dumont
1204 Geneva

With the DUOLAB Subscription

It's even simpler: your Minilab device is provided free of charge for the entire duration of your commitment and becomes permanently yours from your 4th month of subscription.

10 doses of Retinol
Description

Preserved Retinol, Maximum Performance.

Retinol visibly reduces wrinkles and fine lines, plumps the skin, and deeply hydrates. A complete treatment dedicated to skin longevity.

If you're new to retinol, the 0.1% concentration is recommended: active enough to deliver results, gentle enough to respect your skin's tolerance. Retinol is not recommended for pregnant or breastfeeding women.

Our formulas are fragrance-free, silicone-free, with scientifically proven active ingredients. Swiss Made. Yuka Score: 86%

Ingredients

KEY INGREDIENTS:

RETINOL: Accelerates cell renewal and visibly improves skin texture

HYALURONIC ACID: We use 2 hyaluronic acids — one that deeply hydrates and another that plumps the skin

ASTAXANTHIN: A powerful naturally derived antioxidant, capable of protecting the skin against premature aging and oxidative stress

INGRÉDIENTS : AQUA (WATER), CAPRYLIC/CAPRIC TRIGLYCERIDE, GLYCERIN, BUTYLENE GLYCOL, GLYCERYL STEARATE CITRATE, 1,2 HEXANEDIOL, SUCROSE STEARATE, ETHYLHEXYL PALMITATE, RICINUS COMMUNIS (CASTOR) SEED OIL, HYDROGENATED VEGETABLE OIL, GLYCINE SOJA (SOYBEAN) OIL, COCO-CAPRYLATE/CAPRATE, DIPENTAERYTHRITYL HEXACAPRYLATE/HEXACAPRATE, STEARYL HEPTANOATE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, HYDROXYACETOPHENONE, PROPANEDIOL, STEARYL CAPRYLATE, OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES, POLYACRYLATE CROSSPOLYMER-6, XANTHAN GUM, PHYTOSTERYL/OCTYLDODECYL LAUROYL GLUTAMATE, GLYCINE SOJA (SOYBEAN) SEED EXTRACT, SODIUM HYDROXIDE, RETINOL, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, LAMINARIA OCHROLEUCA EXTRACT, CHLAMYDOMONAS REINHARDTII EXTRACT, INULIN LAURYL CARBAMATE, TETRASODIUM GLUTAMATE DIACETATE, HAEMATOCOCCUS PLUVIALIS EXTRACT, CAPRYLYL GLYCOL,TRIHYDROXYSTEARIN, TOCOPHEROL, ALTEROMONAS FERMENT EXTRACT, SCUTELLARIA ALPINA FLOWER/LEAF/STEM EXTRACT, ACETYL HEXAPEPTIDE-1, SODIUM HYALURONATE, POLYGLYCERYL-4 CAPRATE, CITRIC ACID, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL

Clinical Results

Ideal for introducing your skin to retinol:

  • 76% report reduced expression lines
  • 76% firmer skin
  • 77% more toned skin

(Self-assessment, 22 women, ages 45–75, Switzerland)

How to Use

To fully enjoy its benefits, Retinol is used as a 28-day treatment course.

Introduce your Retinol doses gradually to allow your skin to adapt and minimise the risk of irritation. Apply one evening out of three.

Retinol is photosensitising — it makes the skin more sensitive to sun exposure. That's why it should only be applied in the evening. We recommend using sun protection the day after each application to shield your skin from UV rays.

Retinol doses enhance your beauty routine without replacing it: you can continue using your usual products (except those also containing retinol).

Can be combined with our Peptide treatment: Peptide in the morning, Retinol in the evening.

Subscription System

With your DUOLAB subscription, your Minilab is provided free of charge for the entire duration of your commitment. It becomes permanently yours from the 4th month of subscription.

Receive your refills every month, delivered straight to your door, and enjoy 10% off every shipment.

You stay in control: pause, modify, or cancel your subscription at any time from your account.

Featured in leading editorials

Retinol

Retinol

The most powerful retinol is the one that never had time to lose its potency.

Retinol is one of the most effective anti-aging actives — but also one of the most fragile. Exposed to oxygen and time, it can gradually lose its efficacy before it even reaches your skin.

Thanks to DuoLab technology, our retinol formula has 0% degradation — protected in airtight capsules and freshly activated at the moment of application.

Real results, no false promises

What changed for them

  • Before

    After

    “It has been an incredible experience for me. I noticed a change in my complexion after just the first few applications of Duolab; my skin looked more radiant, hydrated, and moisturized. People who know me have made very positive comments about my face. I am delighted! It produced such an incredible change in just a few days. I am excited to see the results with continued use.”

    Olga S.

    August 2026

  • Before

    After

    “I had given up hope! I'd never really seen a difference with any of the other creams I'd tried… and now, for the first time, I'm seeing real, visible results. I have extremely difficult, highly reactive skin, and I'm allergic to so many products. Usually, I spend my time trying to hide my skin issues. And for the first time, other people are complimenting my skin! It's pretty incredible. Thank you Duolab ❤️”

    Anna B.

    August 2026

  • Before

    After

    “I had the privilege of testing the Duolab treatment capsules for about a month, alternating between the Retinol, Peptide, and Eye Treatment formulas. I made sure to apply them in the evening to maximise the effect. I'm impressed by the results and have now become "addicted" — so happy to see the improvement in my skin quality.”

    Impala V.

    August 2026

Clinical Studies

The ultra-powerful Retinol treatment.
Validated by science. Demonstrated by studies. Revealed by your skin.

  • Firmness

    +25%

    Active ingredient degradation

    0%

  • Hydration

    +37%

    Retinol Concentration

    0.3% pure

Measure Result Duration
Wrinkles and fine lines -9.6% 28 days
Firmness +25.0% 28 days
Skin density +21.0% 28 days
Radiance +34.0% 28 days
Hydration +37.0% 28 days

Science & Practical Tips by Duolab

FAQ

Find answers to the most frequently asked questions about our skincare system, cosmetic active ingredients, and eco-responsible refills.

Are your formulas "clean"?

All Duolab formulas follow a strict charter: fragrance-free, silicone-free, free from controversial ingredients, and with a maximum of naturally derived ingredients.

97% naturally derived ingredients in our 4 main treatments.

Yuka score: 86%

Where are Duolab treatments developed and produced?

All our treatments are created and produced in Switzerland. We control every step from formulation to capsule production, allowing us to guarantee full traceability.

Why single-dose format instead of a traditional jar or tube?

The single-dose format is at the core of our proprietary technology — it's the only way to effectively protect active ingredients from any degradation or oxidation.

Each capsule hermetically seals the active ingredients, ensuring zero light exposure and no contact with air. This means that with every application, the active ingredients are 100% effective.

In a traditional jar, oxidation begins the moment it's opened. A retinol in a jar can lose up to 80% of its concentration within six months at 25°C (PubMed data). In a Duolab dose, every active ingredient retains 100% of its potency until application. This is what drives the visible, immediate performance of our treatments.

This format also allows Duolab treatments to be stored for up to 3 years unopened with no loss of efficacy, while a traditional jar lasts 6 to 12 months maximum after opening.

How long can I keep my Duolab treatments after purchase?

Up to 3 years, as long as the dose remains sealed.


Duolab doses perfectly preserve the active ingredients, so you can keep them with no risk of losing efficacy.


Once a dose is opened, we recommend using the contents within the hour.

Why add the Minilab to my skincare routine?

The Minilab is a device that creates a fresh cosmetic emulsion on the spot, just before application.

This freshly prepared emulsion promotes optimal absorption of active ingredients by the skin.

The Minilab is therefore an essential step in ensuring the high quality of Duolab treatments.

Why 2 capsules to make one Duolab treatment?

At Duolab, each active ingredient is stored in the environment best suited to it, in order to fully preserve its stability and efficacy.

That's why our system relies on two separate capsules: one contains a water-based phase, the other an oil-based phase.

Mixed and emulsified only at the moment of application, they release the full power of the active ingredients for optimal efficacy.

How does Minilab maintenance and repair work?

In the event of a technical malfunction, the Minilab must be returned to DuoLab for analysis and repair. A replacement Minilab will be provided as quickly as possible to ensure continuity of your DuoLab experience.

In the event of damage resulting from misuse, accident, or deterioration unrelated to a technical defect, repair or replacement costs may be charged to the customer.